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p53 Apoptosis

Posted on February 14, 2020February 14, 2020 by Ramona Byrd
Caspase 8

Why over-expression of both p63 and p73 induces apoptosis and modulates p53 target genes?

This is observed in a lot of cell types (Moll et al., 2001).

Although it will be possible that this activity merely reflects the ability of protein to have p53 works when sufficiently over-expressed, rising evidence shows that p63 and p73 might be triggered in a reaction to selected apoptotic causes, for example DNA damage, over-expression of E2F1 or activated oncogenes (Katoh et al., 2000; Soengas and Lowe, 2000).

What’s more, the trans-activation domain-deficient isoforms of p63 and p73 are overexpressed in some human tumors (see, for inspection, Moll et al., 2001; Melino et al., 2002; Benard et al., 2003), at which they can act as dominant negatives or interfere with normal p53 function by forming amalgamated complexes with p53 (Moll et al., 2001).

Additionally, a few missense p53 mutants bind p73 and interfere with chemotherapy-induced apoptosis (Bergamaschi et al., 2003; Irwin et al., 2003). These effects may reveal a few p53 mutants’ gain-of-function routines and establish that a mechanism of chemoresistance.

Even though p53 stimulates apoptosis by intricate mechanisms, we centered on the mitochondria, as others, along with our group, scientists established that air borne exposures that cause lung cancer–as an instance, PM and debris, but maybe not inert particulates (e.g., glass rings or ceramic dioxide)–induce apoptosis by triggering the mitochondria-dependent passing pathway (9, 10, 28). We also notice minimal levels of caspase-8 (the death receptor triggered caspase) within our procedure after exposure to either PM or debris.

Antibodies use for apoptosis research are cited here under:

Cat Name Size Price
E13-025-2

p53

50μg 570.00 EUR
4-RPA928Hu02

Recombinant Tumor Protein p53 (P53)

  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • 565.92 EUR
  • 254.00 EUR
  • 1847.20 EUR
  • 682.40 EUR
  • 1264.80 EUR
  • 442.00 EUR
  • 4468.00 EUR
4-RPA928Hu03

Recombinant Tumor Protein p53 (P53)

  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • 565.92 EUR
  • 254.00 EUR
  • 1847.20 EUR
  • 682.40 EUR
  • 1264.80 EUR
  • 442.00 EUR
  • 4468.00 EUR
20-abx121795

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx000156

p53 Phospho-Ser15 (p53 pS15) Antibody

  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • 495.00 EUR
  • 704.00 EUR
  • 217.00 EUR
  • 356.00 EUR
abx139924-01mg

Cellular Tumor Antigen P53 (p53) Antibody

0.1 mg 370.00 EUR
20-abx141063

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx141064

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx141088

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx141162

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx141164

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx141175

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 384.00 EUR
  • 606.00 EUR
  • 230.00 EUR
20-abx142273

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 50 ul
  • 370.00 EUR
  • 606.00 EUR
  • 314.00 EUR
20-abx133358

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx134518

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx134519

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx134520

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx134521

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 356.00 EUR
  • 537.00 EUR
  • 217.00 EUR
20-abx137175

Cellular Tumor Antigen P53 (p53) Antibody

  • 0.2 mg
  • 0.5 mg
  • 100 ug
  • 871.00 EUR
  • 1720.00 EUR
  • 551.00 EUR
abx037925-100ug

Cellular Tumor Antigen P53 (p53) Antibody

100 ug 391.00 EUR
abx032760-400ul

Cellular Tumor Antigen P53 (p53) Antibody

400 ul 523.00 EUR
abx032760-80l

Cellular Tumor Antigen P53 (p53) Antibody

80 µl 286.00 EUR
abx032761-400ul

Cellular Tumor Antigen P53 (p53) Antibody

400 ul 523.00 EUR
abx032761-80l

Cellular Tumor Antigen P53 (p53) Antibody

80 µl 286.00 EUR
abx032762-400ul

Cellular Tumor Antigen P53 (p53) Antibody

400 ul 523.00 EUR
abx032762-80l

Cellular Tumor Antigen P53 (p53) Antibody

80 µl 286.00 EUR
abx032763-400ul

Cellular Tumor Antigen P53 (p53) Antibody

400 ul 523.00 EUR
abx032763-80l

Cellular Tumor Antigen P53 (p53) Antibody

80 µl 286.00 EUR
20-abx008609

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx008610

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx008611

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx008612

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx008613

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx008614

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 300.00 EUR
  • 439.00 EUR
  • 189.00 EUR
20-abx009877

p53 Phospho-Ser15 (p53 pS15) Antibody

  • 100 ul
  • 200 ul
  • 30 ul
  • 314.00 EUR
  • 467.00 EUR
  • 203.00 EUR
abx011309-100ul

Cellular Tumor Antigen P53 (p53) Antibody

100 ul 411.00 EUR
abx012305-100ug

p53 Phospho-Ser15 (p53 pS15) Antibody

100 ug 439.00 EUR
20-abx013359

Cellular Tumor Antigen P53 (p53) Antibody

  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • 314.00 EUR
  • 98.00 EUR
  • 398.00 EUR
  • 495.00 EUR
abx018341-100ug

Cellular Tumor Antigen P53 (P53) Antibody

100 ug 453.00 EUR
abx019148-100ug

Cellular Tumor Antigen P53 (P53) Antibody

100 ug 342.00 EUR
abx020578-02mg

Cellular Tumor Antigen P53 (p53) Antibody

0.2 mg 467.00 EUR
abx444908-100ug

Cellular Tumor Antigen P53 (p53) Antibody

100 ug 453.00 EUR
abx413267-01mg

Cellular Tumor Antigen P53 (p53) Antibody

0.1 mg 439.00 EUR
abx413271-01mg

Cellular Tumor Antigen P53 (p53) Antibody

0.1 mg 439.00 EUR
abx413272-01mg

Cellular Tumor Antigen P53 (p53) Antibody

0.1 mg 439.00 EUR
abx448535-100ug

Cellular Tumor Antigen P53 (p53) Antibody

100 ug 523.00 EUR
abx236083-100ug

Cellular Tumor Antigen P53 (P53) Antibody

100 ug 481.00 EUR
abx236084-100ug

Cellular Tumor Antigen P53 (P53) Antibody

100 ug 551.00 EUR
AF0865

p53 Antibody

200ul 304.00 EUR
AF0877

p53 Antibody

200ul 304.00 EUR
AF0879

p53 Antibody

200ul 304.00 EUR
AF4663

p53 Antibody

200ul 376.00 EUR
AF4664

p53 Antibody

200ul 376.00 EUR
AF6073

p53 Antibody

200ul 304.00 EUR
AF6074

p53 Antibody

200ul 304.00 EUR
AF6078

P53 Antibody

200ul 304.00 EUR
BF0604

p53 Antibody

200ul 376.00 EUR
AF7685

p53 Antibody

200ul 376.00 EUR
AF7686

p53 Antibody

200ul 376.00 EUR
20-abx137497

p53 Antibody

  • 10 ug
  • 1 mg
  • 2 µg
  • 328.00 EUR
  • 6675.00 EUR
  • 230.00 EUR
ABF6073

p53 Antibody

100 ug 438.00 EUR
ABF0865

p53 Antibody

100 ug 438.00 EUR
ABF0877

p53 Antibody

100 ug 438.00 EUR
ABF0879

p53 Antibody

100 ug 438.00 EUR
20-abx263531

p53 Protein

  • 10 ug
  • 2 µg
  • 5 ug
  • 829.00 EUR
  • 411.00 EUR
  • 537.00 EUR
70R-50503

p53 antibody

100 ul 287.00 EUR
70R-50504

p53 antibody

100 ul 287.00 EUR
70R-50505

p53 antibody

100 ul 244.00 EUR
70R-50506

p53 antibody

100 ul 244.00 EUR
70R-50507

p53 antibody

100 ul 244.00 EUR
70R-50508

p53 antibody

100 ul 244.00 EUR
70R-50509

p53 antibody

100 ul 244.00 EUR
70R-50510

p53 antibody

100 ul 244.00 EUR
70R-51663

p53 antibody

100 ul 287.00 EUR
70R-51664

p53 antibody

100 ul 287.00 EUR
70R-51665

p53 antibody

100 ul 244.00 EUR
70R-51666

p53 antibody

100 ul 244.00 EUR
70R-36652

p53 antibody

100 ug 327.00 EUR
70R-37523

p53 antibody

100 ug 273.00 EUR
70R-37524

p53 antibody

100 ug 273.00 EUR
70R-37525

p53 antibody

100 ug 273.00 EUR
70R-37526

p53 antibody

100 ug 273.00 EUR
70R-37528

p53 antibody

100 ug 273.00 EUR
70R-37529

p53 antibody

100 ug 273.00 EUR
70R-37530

p53 antibody

100 ug 273.00 EUR
70R-37531

p53 antibody

100 ug 273.00 EUR
70R-34329

p53 antibody

100 ug 327.00 EUR
70R-34331

p53 antibody

100 ug 327.00 EUR
70R-34333

p53 antibody

100 ug 327.00 EUR
70R-34335

p53 antibody

100 ug 327.00 EUR
70R-34337

p53 antibody

100 ug 327.00 EUR
70R-34339

p53 antibody

100 ug 327.00 EUR
70R-34341

p53 antibody

100 ug 327.00 EUR
70R-34343

p53 antibody

100 ug 327.00 EUR
70R-35291

p53 antibody

100 ug 327.00 EUR
70R-31561

p53 antibody

100 ug 327.00 EUR
ABD6066

p53 Antibody

100 ug 438.00 EUR
33650-100ul

p53 Antibody

100ul 252.00 EUR
33650-50ul

p53 Antibody

50ul 187.00 EUR
48599-100ul

p53 Antibody

100ul 333.00 EUR
48599-50ul

p53 Antibody

50ul 239.00 EUR
48719-100ul

p53 Antibody

100ul 333.00 EUR
48719-50ul

p53 Antibody

50ul 239.00 EUR
10R-10381

P53 antibody

100 ug 435.00 EUR
10-2559

p53 antibody

250 ug 492.00 EUR
10-2560

p53 antibody

250 ug 492.00 EUR
10-2561

p53 antibody

250 ug 492.00 EUR
10-2562

p53 antibody

250 ug 492.00 EUR
10R-6721

p53 antibody

100 ug 651.00 EUR
10R-6772

p53 antibody

1 ml 402.00 EUR
10R-7889

p53 antibody

100 ug 305.00 EUR
10R-8113

p53 antibody

100 ug 435.00 EUR
10R-8591

p53 antibody

100 ul 393.00 EUR
10R-P159A

p53 antibody

100 ug 543.00 EUR
10R-P160A

p53 antibody

100 ug 457.00 EUR
30R-3131

p53 protein

50 ug 257.00 EUR
30R-3187

p53 protein

50 ug 257.00 EUR
3036R-100

p53 Antibody

316.00 EUR
3036R-30T

p53 Antibody

146.00 EUR
10R-1910

p53 antibody

100 ul 403.00 EUR
10R-2361

p53 antibody

2 x 25 ug 359.00 EUR
10R-2391

p53 antibody

5 mL 265.00 EUR
20R-1436

p53 antibody

100 ug 673.00 EUR
20R-1619

p53 antibody

100 ug 813.00 EUR
20R-1950

p53 antibody

50 ug 281.00 EUR
20R-1951

p53 antibody

50 ug 281.00 EUR
20R-1952

p53 antibody

50 ug 281.00 EUR
20R-1954

p53 antibody

50 ug 281.00 EUR
20R-1955

p53 antibody

50 ug 281.00 EUR
20R-1956

p53 antibody

50 ug 281.00 EUR
20R-1957

p53 antibody

50 ug 281.00 EUR
20R-2264

p53 antibody

50 ug 281.00 EUR
20R-2265

p53 antibody

50 ug 281.00 EUR
20R-2266

p53 antibody

50 ug 281.00 EUR
20R-2267

p53 antibody

50 ug 281.00 EUR
20R-2268

p53 antibody

50 ug 281.00 EUR
20R-2269

p53 antibody

50 ug 281.00 EUR
20R-2270

p53 antibody

50 ug 281.00 EUR
20R-2271

p53 antibody

50 ug 281.00 EUR
20R-2904

p53 antibody

100 ul 393.00 EUR
70R-11573

p53 antibody

100 ug 403.00 EUR
70R-15485

p53 antibody

100 ug 327.00 EUR
DF6066

p53 Antibody

200ul 304.00 EUR
DB-002-0.05

Anti-p53

50 μl 302.00 EUR
DB-002-0.1

Anti-p53

100 μl 477.00 EUR
DB-026-0.1

Anti-p53

100 μl 204.00 EUR
DB-026-0.2

Anti-p53

200 μl 286.00 EUR
DB-026-0.5

Anti-p53

500 μl 368.00 EUR
DB-026-1

Anti-p53

1 ml 586.00 EUR
DB-026-RTU-15

Anti-p53

15 ml 338.00 EUR
p53 mediated Apoptosis

p53 Antibody

ABF6073 Lifescience Market 100 ug

p53 Antibody

ABD6066 Lifescience Market 100 ug

p53 Antibody

ABF0865 Lifescience Market 100 ug

p53 Antibody

ABF0877 Lifescience Market 100 ug

p53 Antibody

ABF0879 Lifescience Market 100 ug

anti-p53

LF-PA0050 Abfrontier 100 ul

p53 Antibody

P1022-01m SAB 0.1m

p53 Antibody

P1022-1ml SAB 1ml

p53- Luc

PVT10836 Lifescience Market 2 ug

p53- His2

PVT11251 Lifescience Market 2 ug

P53- GFP

PVT11397 Lifescience Market 2 ug

anti-p53

YF-PA15085 Abfrontier 50 ug

anti-p53

YF-PA15087 Abfrontier 50 ug

anti-p53

YF-PA15088 Abfrontier 100 ul

anti-p53

YF-PA15089 Abfrontier 100 ug

anti-p53

YF-PA15090 Abfrontier 100 ug

anti-p53

YF-PA24879 Abfrontier 50 ul

Human Acetylated p53(Acetylated p53) ELISA Kit

EH4216 FN Test 96T

p53/TP53/ Rat p53/ TP53 ELISA Kit

ELA-E0928r Lifescience Market 96 Tests

Cellular Tumor Antigen P53 (p53) Antibody (Biotin)

abx413268-01mg Abbexa 0.1 mg

Cellular Tumor Antigen P53 (p53) Antibody (FITC)

abx413269-01mg Abbexa 0.1 mg

Cellular Tumor Antigen P53 (p53) Antibody (RPE)

abx413270-100tests Abbexa 100 tests

Cellular Tumor Antigen P53 (p53) Antibody (ALP)

abx442310-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (APC)

abx442591-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (Biotin)

abx442872-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (FITC)

abx443152-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (HRP)

abx443432-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (PerCP)

abx443994-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (RPE)

abx444275-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (Streptavidin)

abx444556-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ALP)

abx446373-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (APC)

abx446374-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (PerCP)

abx446379-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (RPE)

abx446380-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (Streptavidin)

abx446381-100ug Abbexa 100 ug

Human Acetylated p53 & Total p53 ELISA Kit

QY-E05440 Qayee Biotechnology 96T

Human p53/tumor protein,p53/TP53 ELISA Kit

201-12-1712 SunredBio 96 tests

Human p53 Phospho-Ser15 (p53 pS15) ELISA Kit

abx257458-96tests Abbexa 96 tests

Human Total P53(Tumor Protein p53) ELISA Kit

EH3898 FN Test 96T

Rabbit p53/tumor protein,p53/TP53 ELISA Kit

CN-00573R1 ChemNorm 96T

Rabbit p53/tumor protein,p53/TP53 ELISA Kit

CN-00573R2 ChemNorm 48T

Human p53/tumor protein, p53/TP53 ELISA Kit

CSB-E08334h-24T Cusabio 1 plate of 24 wells

Human p53/tumor protein, p53/TP53 ELISA Kit

1-CSB-E08334h Cusabio
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each

Rat p53/tumor protein, p53/TP53 ELISA Kit

CSB-E08336r-24T Cusabio 1 plate of 24 wells

Rat p53/tumor protein, p53/TP53 ELISA Kit

1-CSB-E08336r Cusabio
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each

Mouse p53/tumor protein,p53/TP53 ELISA Kit

CN-02303M1 ChemNorm 96T

Mouse p53/tumor protein,p53/TP53 ELISA Kit

CN-02303M2 ChemNorm 48T

Human p53/tumor protein,p53/TP53 ELISA Kit

CN-03353H1 ChemNorm 96T

Human p53/tumor protein,p53/TP53 ELISA Kit

CN-03353H2 ChemNorm 48T

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 390)

abx440062-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 488)

abx440343-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 565)

abx440624-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 594)

abx440905-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 633)

abx441186-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 655)

abx441467-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 680)

abx441748-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 700)

abx442029-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 390)

abx446365-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 488)

abx446366-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 565)

abx446367-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 594)

abx446368-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 633)

abx446369-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 655)

abx446370-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 680)

abx446371-100ug Abbexa 100 ug

Cellular Tumor Antigen P53 (p53) Antibody (ATTO 700)

abx446372-100ug Abbexa 100 ug

Human p53/tumor protein(p53/TP53)ELISA Kit

GA-E1728HM-48T GenAsia Biotech 48T

Human p53/tumor protein(p53/TP53)ELISA Kit

GA-E1728HM-96T GenAsia Biotech 96T

Mouse p53/tumor protein(p53/TP53)ELISA Kit

GA-E0422MS-48T GenAsia Biotech 48T

Mouse p53/tumor protein(p53/TP53)ELISA Kit

GA-E0422MS-96T GenAsia Biotech 96T

Rabbit p53/tumor protein,p53/TP53 ELISA Kit

GA-E0162RB-48T GenAsia Biotech 48T

Rabbit p53/tumor protein,p53/TP53 ELISA Kit

GA-E0162RB-96T GenAsia Biotech 96T

Rat p53/tumor protein(p53/TP53)ELISA Kit

GA-E0080RT-48T GenAsia Biotech 48T

Rat p53/tumor protein(p53/TP53)ELISA Kit

GA-E0080RT-96T GenAsia Biotech 96T

Human p53/tumor protein(p53/TP53)ELISA Kit

QY-E04715 Qayee Biotechnology 96T

Human Phospho ser15 P53 & Total p53 ELISA Kit

QY-E05441 Qayee Biotechnology 96T

Rat p53/tumor protein(p53/TP53)ELISA Kit

QY-E11573 Qayee Biotechnology 96T

Mouse p53/tumor protein(p53/TP53)ELISA Kit

QY-E21135 Qayee Biotechnology 96T

Rabbit p53/tumor protein,p53/TP53 ELISA Kit

QY-E30138 Qayee Biotechnology 96T

p53 Blocking Peptide

3036RBP-50 Biovision

P53 Monoclonal Antibody

27021-100ul SAB 100ul

P53 Monoclonal Antibody

27021-50ul SAB 50ul

Phospho-p53 antibody

70R-11881 Fitzgerald 100 ug

Recombinant Human p53

7-05785 CHI Scientific 2µg

Recombinant Human p53

7-05786 CHI Scientific 5µg

Recombinant Human p53

7-05787 CHI Scientific 10µg

p53 antibody (Thr81)

70R-31503 Fitzgerald 100 ug

p53 Mouse mAb

A10610-100ul Abclonal 100 ul

p53 Mouse mAb

A10610-200ul Abclonal 200 ul

p53 Mouse mAb

A10610-20ul Abclonal 20 ul

p53 Mouse mAb

A10610-50ul Abclonal 50 ul

p53 Rabbit mAb

A11012-100ul Abclonal 100 ul

p53 Rabbit mAb

A11012-200ul Abclonal 200 ul

p53 Rabbit mAb

A11012-20ul Abclonal 20 ul

p53 Rabbit mAb

A11012-50ul Abclonal 50 ul

p53 Blocking Peptide

33R-10444 Fitzgerald 50 ug

p53 Blocking Peptide

33R-10604 Fitzgerald 50 ug

Phospho-p53 Antibody

3515-100 Biovision

Anti-p53 Purified

11-114-C025 ExBio 0.025 mg

Anti-p53 Purified

11-114-C100 ExBio 0.1 mg

Anti-p53 FITC

1F-114-C025 ExBio 0.025 mg

Anti-p53 FITC

1F-114-C100 ExBio 0.1 mg

p53 antibody (HRP)

60R-2272 Fitzgerald 100 ug

p53 antibody (FITC)

60R-2273 Fitzgerald 100 ug

p53 antibody (biotin)

60R-2274 Fitzgerald 100 ug

p53 antibody (FITC)

61R-1897 Fitzgerald 1 ml

Mutant p53 Antibody

49815-100ul SAB 100ul

Mutant p53 Antibody

49815-50ul SAB 50ul

p53 DINP1 Antibody

49906-100ul SAB 100ul

p53 DINP1 Antibody

49906-50ul SAB 50ul

p53 Polyclonal Antibody

41307-100ul SAB 100ul

p53 Polyclonal Antibody

41307-50ul SAB 50ul

p53 Polyclonal Antibody

41308-100ul SAB 100ul

p53 Polyclonal Antibody

41308-50ul SAB 50ul

p53 Polyclonal Antibody

41309-100ul SAB 100ul

p53 Polyclonal Antibody

41309-50ul SAB 50ul

p53 Polyclonal Antibody

41310-100ul SAB 100ul

p53 Polyclonal Antibody

41310-50ul SAB 50ul

p53 Polyclonal Antibody

41311-100ul SAB 100ul

p53 Polyclonal Antibody

41311-50ul SAB 50ul

p53 Polyclonal Antibody

41312-100ul SAB 100ul

p53 Polyclonal Antibody

41312-50ul SAB 50ul

p53 Polyclonal Antibody

41313-100ul SAB 100ul

p53 Polyclonal Antibody

41313-50ul SAB 50ul

p53 Polyclonal Antibody

41734-100ul SAB 100ul

p53 Polyclonal Antibody

41734-50ul SAB 50ul

p53 Polyclonal Antibody

41875-100ul SAB 100ul

p53 Polyclonal Antibody

41875-50ul SAB 50ul

p53 Polyclonal Antibody

41876-100ul SAB 100ul

p53 Polyclonal Antibody

41876-50ul SAB 50ul

Polyclonal p53 Antibody

APR00006G Leading Biology 0.1mg

p53 Blocking Peptide

DF6066-BP Affbiotech 1mg

p53 Rabbit pAb

A0263-100ul Abclonal 100 ul

p53 Rabbit pAb

A0263-200ul Abclonal 200 ul

p53 Rabbit pAb

A0263-20ul Abclonal 20 ul

p53 Rabbit pAb

A0263-50ul Abclonal 50 ul

p53 antibody (Ser392)

70R-35009 Fitzgerald 100 ug

p53 antibody (Ser20)

70R-35201 Fitzgerald 100 ug

p53 antibody (Ser6)

70R-37173 Fitzgerald 100 ug

p53 antibody (Ser15)

70R-37174 Fitzgerald 100 ug

p53 antibody (Thr18)

70R-37175 Fitzgerald 100 ug

p53 antibody (Ser33)

70R-37177 Fitzgerald 100 ug

p53 antibody (Ser37)

70R-37178 Fitzgerald 100 ug

p53 antibody (Ser46)

70R-37179 Fitzgerald 100 ug

p53 antibody (Ser315)

70R-37180 Fitzgerald 100 ug

P53 antibody (Ser20)

70R-37414 Fitzgerald 100 ug

P53 antibody (Ser37)

70R-37415 Fitzgerald 100 ug

p53 antibody (Thr387)

70R-32611 Fitzgerald 100 ug

p53 antibody (Ser376)

70R-32612 Fitzgerald 100 ug

p53 antibody (Ser366)

70R-32613 Fitzgerald 100 ug

p53 antibody (Ser378)

70R-32614 Fitzgerald 100 ug

p53 antibody (Ser15)

70R-34328 Fitzgerald 100 ug

p53 antibody (Ser315)

70R-34330 Fitzgerald 100 ug

p53 antibody (Ser33)

70R-34332 Fitzgerald 100 ug

p53 antibody (Ser37)

70R-34334 Fitzgerald 100 ug

p53 antibody (Ser46)

70R-34336 Fitzgerald 100 ug

p53 antibody (Ser6)

70R-34338 Fitzgerald 100 ug

p53 antibody (Ser9)

70R-34340 Fitzgerald 100 ug

p53 antibody (Thr18)

70R-34342 Fitzgerald 100 ug

p53 (pS315) Antibody

20-abx009876 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pT55) Antibody

abx219057-100ug Abbexa 100 ug

p53 (pS392) Antibody

abx219058-100ug Abbexa 100 ug

p53 (pT18) Antibody

20-abx119197 Abbexa
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p53 (pS33) Antibody

20-abx119530 Abbexa
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p53 (pS37) Antibody

20-abx119531 Abbexa
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p53 (pS6) Antibody

20-abx119532 Abbexa
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

p53 (AcK386) Antibody

20-abx121192 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pS392) Antibody

20-abx121792 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (AcK319) Antibody

20-abx121793 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (AcK381) Antibody

20-abx121794 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

P53 AIP1 Antibody

abx037562-100ug Abbexa 100 ug

Human P53 Protein

20-abx060205 Abbexa
  • 100 ug
  • 1 mg
  • 2.5 mg
  • 2 mg

p53 (pS6) Antibody

20-abx133354 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pS9) Antibody

20-abx133355 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pT18) Antibody

20-abx133356 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pS20) Antibody

20-abx133357 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pS33) Antibody

20-abx134516 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pS37) Antibody

20-abx134517 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 Blocking Peptide

20-abx161505 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx162067 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx162208 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx162209 Abbexa
  • 1 mg
  • 5 mg

p53 (pS392) Antibody

abx139925-01mg Abbexa 0.1 mg

p53 Antibody (FITC)

abx139926-01mg Abbexa 0.1 mg

p53 (pS46) Antibody

20-abx141020 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (AcK370) Antibody

20-abx141163 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (AcK382) Antibody

20-abx141165 Abbexa
  • 100 ul
  • 200 ul
  • 30 ul

p53 (pS46) Antibody

abx012295-100ug Abbexa 100 ug

p53 (pS20) Antibody

abx012297-100ug Abbexa 100 ug

p53 (pS9) Antibody

abx012298-100ug Abbexa 100 ug

p53 (pS366) Antibody

abx012299-100ug Abbexa 100 ug

p53 (pS392) Antibody

abx012300-100ug Abbexa 100 ug

p53 (pS315) Antibody

abx012304-100ug Abbexa 100 ug

p53 (pS20) Antibody

abx031895-400ul Abbexa 400 ul

p53 (pS20) Antibody

abx031895-80l Abbexa 80 µl

p53 (pS315) Antibody

abx031896-400ul Abbexa 400 ul

p53 (pS315) Antibody

abx031896-80l Abbexa 80 µl

P53 (pS9) Antibody

abx031898-400ul Abbexa 400 ul

P53 (pS9) Antibody

abx031898-80l Abbexa 80 µl

p53 (pT18) Antibody

abx031899-400ul Abbexa 400 ul

p53 (pT18) Antibody

abx031899-80l Abbexa 80 µl

p53 (pT55) Antibody

abx032008-400ul Abbexa 400 ul

p53 (pT55) Antibody

abx032008-80l Abbexa 80 µl

p53 Blocking Peptide

20-abx061761 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx061762 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx061786 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx061860 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx061862 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx061873 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx063380 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx063381 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx063383 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx063384 Abbexa
  • 1 mg
  • 5 mg

p53 Blocking Peptide

20-abx063385 Abbexa
  • 1 mg
  • 5 mg

p53 Mutant Protein

20-abx263550 Abbexa
  • 10 ug
  • 2 µg
  • 5 ug

P53 recombinant protein

E62C02301 EnoGene 20ug

P53 Polyclonal Antibody

EA173-100ul ELK Biotech 100ul

P53 Polyclonal Antibody

EA173-50ul ELK Biotech 50ul

Anti-p53 Antibody

CI1060 BosterBio 50ug/50ul

p53 Blocking Peptide

AF0865-BP Affbiotech 1mg

p53 Blocking Peptide

AF0877-BP Affbiotech 1mg

p53 Blocking Peptide

AF0879-BP Affbiotech 1mg

p53 Blocking Peptide

AF4663-BP Affbiotech 1mg

p53 Blocking Peptide

AF4664-BP Affbiotech 1mg

p53 Blocking Peptide

AF6073-BP Affbiotech 1mg

p53 Blocking Peptide

AF6074-BP Affbiotech 1mg

P53 Blocking Peptide

AF6078-BP Affbiotech 1mg

p53(PAb122) Antibody

BNUB0338-100 Biotium 100uL

p53(PAb122) Antibody

BNUB0338-500 Biotium 500uL

p53(PAb122) Antibody

BNUM0338-50 Biotium 50uL

p53 Blocking Peptide

BF0604-BP Affbiotech 1mg

p53 Mouse mAb

BF9304 Lifescience Market 100 ug

p53(PAb122) Antibody

BNC040338-100 Biotium 100uL

p53(PAb122) Antibody

BNC040338-500 Biotium 500uL

p53(PAb122) Antibody

BNC610338-100 Biotium 100uL

p53(PAb122) Antibody

BNC610338-500 Biotium 500uL

p53(PAb122) Antibody

BNC470338-100 Biotium 100uL

p53(PAb122) Antibody

BNC470338-500 Biotium 500uL

p53(PAb122) Antibody

BNC550338-100 Biotium 100uL

p53(PAb122) Antibody

BNC550338-500 Biotium 500uL

p53(PAb122) Antibody

BNC050338-100 Biotium 100uL

p53(PAb122) Antibody

BNC050338-500 Biotium 500uL

p53(PAb122) Antibody

BNC400338-100 Biotium 100uL

p53(PAb122) Antibody

BNC400338-500 Biotium 500uL

p53(PAb122) Antibody

BNC430338-100 Biotium 100uL

p53(PAb122) Antibody

BNC430338-500 Biotium 500uL

p53 Antibody (Biotin)

abx446375-100ug Abbexa 100 ug

p53 Antibody (FITC)

abx446376-100ug Abbexa 100 ug

p53 Antibody (HRP)

abx446377-100ug Abbexa 100 ug

p53(PAb122) Antibody

BNC800338-100 Biotium 100uL

p53(PAb122) Antibody

BNC800338-500 Biotium 500uL

p53(PAb122) Antibody

BNC810338-100 Biotium 100uL

p53(PAb122) Antibody

BNC810338-500 Biotium 500uL

p53(PAb122) Antibody

BNCP0338-250 Biotium 250uL

p53(PAb122) Antibody

BNCR0338-250 Biotium 250uL

p53(PAb122) Antibody

BNCA0338-250 Biotium 250uL

p53(PAb122) Antibody

BNCAP0338-100 Biotium 100uL

p53(PAb122) Antibody

BNCAP0338-500 Biotium 500uL

p53(PAb122) Antibody

BNCH0338-100 Biotium 100uL

p53(PAb122) Antibody

BNCH0338-500 Biotium 500uL

p53(PAb122) Antibody

BNC940338-100 Biotium 100uL

p53(PAb122) Antibody

BNC940338-500 Biotium 500uL

p53(PAb122) Antibody

BNC700338-100 Biotium 100uL

p53(PAb122) Antibody

BNC700338-500 Biotium 500uL

p53(PAb122) Antibody

BNCB0338-100 Biotium 100uL

p53(PAb122) Antibody

BNCB0338-500 Biotium 500uL

p53(PAb122) Antibody

BNC880338-100 Biotium 100uL

p53(PAb122) Antibody

BNC880338-500 Biotium 500uL

p53(PAb122) Antibody

BNC680338-100 Biotium 100uL

p53(PAb122) Antibody

BNC680338-500 Biotium 500uL

p53 Blocking Peptide

AF7685-BP Affbiotech 1mg

p53 Blocking Peptide

AF7686-BP Affbiotech 1mg

p53 Polyclonal Antibody

ABP53071-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP53071-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP53071-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP53072-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP53072-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP53072-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP53235-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP53235-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP53235-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP53236-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP53236-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP53236-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP53237-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP53237-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP53237-02ml Abbkine 0.2ml

p53 Monoclonal Antibody

ABM40052-003ml Abbkine 0.03ml

p53 Monoclonal Antibody

ABM40052-01ml Abbkine 0.1ml

p53 Monoclonal Antibody

ABM40052-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP52117-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP52117-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP52117-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP52118-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP52118-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP52118-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP52119-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP52119-01ml Abbkine 0.1ml

p53 Polyclonal Antibody

ABP52119-02ml Abbkine 0.2ml

p53 Polyclonal Antibody

ABP52120-003ml Abbkine 0.03ml

p53 Polyclonal Antibody

ABP52120-01ml Abbkine 0.1ml

p53-dependent transcription

Among the key signs of the study is that inhibitors of the p53-dependent transcriptional action (pifithrin-α, E6 protein overexpression, or p53 dominant adverse gene expression) blocked PM-induced mitochondrial dysfunction, as assessed by Δψm along with caspase-9 activation, also as apoptosis, as evaluated by annexin V staining and DNA fragmentation.

Furthermore, the protecting effects reported in A549-E6 cells exposed to PM from the current study are like the effects observed from radiation- related and asbestos-induced cytotoxicity .

The p53 tumor suppressor protein has been also well known for its job as a transcription factor which modulates the expression of stress response genes and mediates quite a few anti-proliferative processes.

  • Underscoring its importance at the regulation of proliferative homeostasis, it is the most frequently mutated tumor suppressor in human cancers.
  • It’s known to mediate its effects through the activation of genes regulating cell cycle checkpoints, DNA damage and repair, and apoptosis.
  • For apoptosis specifically, p53 enriches the manifestation Bcl-2 relatives like Bax, BID, PUMA, along with Noxa.3-6 It’s also known to regulate APAF-1, a coactivator of this apoptosis initiator Caspase-9.
  • Though its position for a mediator of transcription is well recognized, some studies seem to suggest that p53 could affect apoptosis by means of publication transcription-independent pathways.

Spots of low/insufficient oxygen (hypoxia) really are a pathophysiological characteristic of most solid tumors (inch ).

It has been demonstrated conclusively that people using significant heights of tumor hypoxia possess a worse prognosis regardless of therapy modality (2 – 4). Within a tumor, gradients of oxygen levels exist, which are likely to accomplish whole anoxia in avascular are as.

Cells exposed to severe hypoxia are involved in Aopotosis.

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Categories

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Health Pediatric Surgical Research Output in Germany in the Last 30 Years - An Assessment and International Comparison of Three Dedicated Paediatric Surgical Journals. Spontaneous ventilation versus mechanical ventilation during video-assisted thoracoscopic surgery for spontaneous pneumothorax: a study protocol for multicenter randomized controlled trial. well-being and social relations in a changing neighbourhood: protocol for a prospective
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